Clinical progression refers to the natural course of a disease or condition in an individual patient over time. This includes the development and evolution of symptoms, the impact on functioning and quality of life, and the response to treatment. Understanding the clinical progression of a disease is important for predicting outcomes, optimizing treatment strategies, and monitoring the effectiveness of interventions. Researchers in this area may study factors that influence disease progression, develop tools for tracking changes in patients over time, and evaluate the effectiveness of different treatment approaches. Ultimately, the goal of research in clinical progression is to improve outcomes and quality of life for patients with various health conditions.